Pregnancy Outcomes and Clinical Management in Women with Undifferentiated Connective Tissue Dysplasia: A Systematic Approach

Abstract

Undifferentiated Connective Tissue Dysplasia (UCTD) is an underrecognized condition characterized by structural abnormalities in connective tissue, presenting variably across organ systems. In women of reproductive age, UCTD can significantly impact pregnancy outcomes, including risks of miscarriage, cervical insufficiency, and vascular complications. This paper presents a structured clinical approach to optimize pregnancy management in women with UCTD, based on current literature, pathophysiological insights, and multidisciplinary care protocols.