THE ROLE OF RADIODIAGNOSIS IN ASSESSING NATURAL AGING OF THE BRAIN

Abstract

Study the human brain in vivo, with the help of radiation research methods, understanding the nature and location of age-related changes is of increasing interest. Changes in brain volume over time in healthy adults are highly variable. Although brain volume loss is widespread, its extent varies in different brain regions. Brain aging is based on many factors, and they are expressed differently in each individual. Brain volume decreases with age, even in relatively healthy adults without evidence of general cognitive decline. Brain aging is nonlinear, and no sex differences in age-related trends in brain aging have been observed. Individual differences in the degree and type of changes are substantial and, in some important brain regions, are enhanced or mediated to some extent by vascular risk factors.